[HTML][HTML] Comparison of the degree of gastric mucosal injury between patients who are receiving dual antiplatelet therapy or single antiplatelet therapy

Y Shimada, M Hojo, Y Kita, Y Ikeda, S Sato, A Murata… - Diagnostics, 2022 - mdpi.com
… of gastric mucosal injury in patients taking low-dose aspirin in … pKa 3.5) and in the highly
acidic stomach (pH 1–2) it exists in … the platelet aggregation effect of clopidogrel [25,26], but at

[HTML][HTML] Low-dose aspirin-induced upper gastrointestinal bleed and ulceration

VT Parikh, MK Shah, SD Gupta… - National Journal of …, 2023 - journals.lww.com
… LDA therapy can also increase the risk of upper GI side effects, including acute mucosal
lesions, … Severe upper gastrointestinal bleeding with gastric ulcer and anaemia secondary to …

[HTML][HTML] Combination of Panax notoginseng saponins and aspirin potentiates platelet inhibition with alleviated gastric injury via modulating arachidonic acid …

W Wang, L Yang, L Song, M Guo, C Li, B Yang… - Biomedicine & …, 2021 - Elsevier
… and platelet aggregation and led to increased platelet inhibition … low dose of 50−75 mg daily
[8], which compromise clinical … platelets were lysed with ice-cold 100 mM Tris-HCl (PH 7.5) …

[HTML][HTML] Pharmacological Efficacy and Gastrointestinal Safety of Different Aspirin Formulations for Cardiovascular Prevention: A Narrative Review

B Clerici, M Cattaneo - Journal of Cardiovascular Development and …, 2023 - mdpi.com
… Due to its inhibitory effect on platelet function, aspirin is … with low-dose aspirin was 40–80%
higher than in placebo-… Plain aspirin is absorbed in the stomach, where the low pH

Xiaojianzhong decoction attenuates aspirin-induced gastric mucosal injury via the PI3K/AKT/mTOR/ULK1 and AMPK/ULK1 pathways

T Chen, S Bao, J Chen, J Zhang, H Wei, X Hu… - Pharmaceutical …, 2023 - Taylor & Francis
… -dose (6 g/kg), XJZD low-dose (3 g/kg) and omeprazole (20 … the synthesis of gastric mucosa,
attenuate the digestive effect of … (pH 7.4) for 15 min each. The tissues were then dehydrated …

[HTML][HTML] Pharmacokinetic and pharmacodynamic profiles of a novel phospholipid-aspirin complex liquid formulation and low dose enteric-coated aspirin: results from a …

F Franchi, DJ Schneider, J Prats, W Fan… - Journal of Thrombosis …, 2022 - Springer
… for acetylsalicylic acid and salicylic acid, platelet aggregation in … low dose aspirin is the
foundational antithrombotic therapypH environments, such as the stomach, thereby limiting free …

[HTML][HTML] Panax quinquefolius saponins combined with dual antiplatelet therapy enhanced platelet inhibition with alleviated gastric injury via regulating eicosanoids …

W Wang, L Song, L Yang, C Li, Y Ma, M Xue… - … Medicine and Therapies, 2023 - Springer
… with dual antiplatelet therapy (DAPT) on platelet aggregation, … 2.5% glutaraldehyde (pH
= 7.2) at room temperature for 3 … taking low dose ASA show endoscopic gastric erosions [48], …

Optimizing antithrombotic therapy in patients with coexisting cardiovascular and gastrointestinal disease

AH Talasaz, P Sadeghipour, L Ortega-Paz… - Nature Reviews …, 2024 - nature.com
… motility of the gastrointestinal system, gastrointestinal pH, the … Monitoring of platelet function
in patients at high risk of … of being at high risk of bleeding and who were receiving low-dose

Further Review of Aspirin in the Treatment of Kawasaki Disease

F Jiao, J Wang, J Feng, X Kong… - Asian Journal of …, 2022 - asian.go4publish.com
gastrointestinal pHlow dose (3-5)mg/(kg·d) in the recovery phase. Light transmission was
applied Aggregometry (LTA) determined platelet aggregation rates at different doses of aspirin

[HTML][HTML] Low-dose PPI to prevent bleeding after ESD: A multicenter randomized controlled study

L Yang, J Qi, W Chen, Q Guo, R Xie, Z Zhao… - Biomedicine & …, 2021 - Elsevier
… diagnosis of gastric mucosal lesions after ESD treatment were … When the pH falls below 6,
platelet aggregation and blood … who taking drugs such as aspirin, NSAIDs, or anticoagulants, …